S1R agonist 2 NEW
Price | $39 | $93 | $148 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: S1R agonist 2 | CAS No.: 150085-21-5 |
Purity: 99.04% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | S1R agonist 2 |
Description | S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity. |
In vitro | S1R agonist 2 (Compound 8b; 0.1-5 μM) significantly increases neurite growth induced by nerve growth factor (NGF) in a dose-dependent manner and has a neuroprotective effect on NMDA stimulation in SHSY5Y cells. At 1 μM (24 hours), it significantly inhibits cell damage induced by Rotenone in SHSY5Y cells and shows no cytotoxicity to A549, LoVo, and Panc-1 cells (0-10 μM; 24-72 hours).[1] |
Storage | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/mL (161.58 mM) |
Inhibitors Related | Allopurinol | Acetylcysteine | Mephenesin | Halothane | Tempol | Inosine | Amitriptyline hydrochloride | Lycopene | Ethyl cinnamate | Riluzole | Rifamycin S | O-Phospho-L-serine |
Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neuroprotective Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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