S55746 NEW
Price | $51 | $74 | $110 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: S55746 | CAS No.: 1448584-12-0 |
Purity: 97.14% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | S55746 |
Description | S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM). |
In vitro | S55746 selectively causes apoptosis through BCL-2 inhibition in a BAX/BAK-dependent manner. S55746 (0-1 μM) effectively and selectively induces cell death [1]. |
In vivo | S55746 is a potent and well-tolerated oral BCL-2 inhibitor, effective even at doses up to 300 mg/kg. At doses of 20-100 mg/kg (p.o.), S55746 inhibits xenograft growth in RS4 [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 44 mg/mL (61.9 mM), Sonication is recommended. |
Keywords | inhibit | S-55746 | BCL-201 | Inhibitor | S 55746 | Bcl-2 Family | BCL 201 | S55746 | BLC-201 | BCL201 | BLC 201 |
Inhibitors Related | Gossypol (acetic acid) | (S)-(+)-Ibuprofen | Allethrin | Navitoclax | Docetaxel trihydrate | Gossypol | Triacetylresveratrol | Diphenyl disulfide | Lisaftoclax | Venetoclax | (E)-Ferulic acid | Thymoquinone |
Related Compound Libraries | Highly Selective Inhibitor Library | Bioactive Compound Library | ReFRAME Related Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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$632.00/25mg |
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TargetMol Chemicals Inc.
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2024-10-28 | |
$51.00/1mg |
VIP3Y
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TargetMol Chemicals Inc.
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2024-11-19 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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