SEP-363856 hydrochloride NEW
| Price | $64 | $156 | $255 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: SEP-363856 hydrochloride | CAS No.: 1310422-41-3 |
| Purity: 99.99% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名称 | SEP-363856 hydrochloride |
| 描述 | SEP-363856 hydrochloride (SEP-856 hydrochloride) is an orally active, CNS-active psychotropic agent with a unique non-D2/5-HT2A mechanism of action, demonstrating antipsychotic-like effects and potential for schizophrenia treatment. |
| 体外活性 | SEP-856 (10μM) specifically inhibits α2A, α2B, D2, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C and 5-HT7> 50% receptor. |
| 体内活性 | SEP-856 (0.3, 1, and 10 mg/kg, i.p.) is CNS active and exhibits a behavioral signature similar to known antipsychotic drugs. PCP-induced hyperactivity is significantly reduced by SEP-856 (0.3, 1, and 10 mg/kg, orally once). Oral SEP-856 administration (1, 3, and 10 mg/kg) produces a dose-dependent decrease in REM sleep, increase in latency to REM sleep, and increase in cumulative wake (W) time. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 55 mg/mL (250.31 mM), Sonication is recommended. |
| 关键字 | Inhibitor | SEP 856 | SEP856 | SEP-363856 Hydrochloride | SEP363856 | SEP-856 Hydrochloride | SEP 363856 hydrochloride | 5-hydroxytryptamine Receptor | inhibit | Serotonin Receptor | SEP363856 Hydrochloride | SEP363856 hydrochloride | SEP-363856 | SEP 363856 | SEP-856 | SEP856 Hydrochloride | SEP 363856 Hydrochloride | SEP 856 Hydrochloride | 5-HT Receptor |
| 相关产品 | Serotonin hydrochloride | Alverine citrate | Olanzapine | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Mirtazapine | Amitriptyline hydrochloride | Cloperastine hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine |
| 相关库 | 疼痛相关化合物库 | 经典已知活性库 | 神经退行性疾病化合物库 | 抗阿尔茨海默症化合物库 | 膜蛋白靶向化合物库 | 抗癌临床化合物库 | 药物功能重定位化合物库 | 已知活性化合物库 | GPCR靶点分子库 | 抗癌药物库 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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