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Postion:Product Catalog >Tenalisib
Tenalisib
  • Tenalisib

Tenalisib NEW

Price $32 $45 $74
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Tenalisib CAS No.: 1639417-53-0
Purity: 99.71% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTenalisib
DescriptionTenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)
In vitroIn both HEL-RS and HEL-RR cells, Tenalisib exhibits modest proliferation inhibition (33-46% inhibition @ 10 μM). Addition of 10 μM tenalisib to ruxolitinib is synergistic resulting in a near-complete inhibition of proliferation (>90% for HEL-RS and >70% for HEL-RR). Addition of 5 μM tenalisib, 4 h prior to the addition of ruxolitinib results in a significant reduction in EC50of ruxolitinib (5.8 μM) in HEL-RR cells.
In vivoSingle agent(Tenalisib) activity is evident in difficult-to-treat subjects at ≥ 200 mg BID[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (240.72 mM)
KeywordsRP-6530 | PI3K | Phosphoinositide 3-kinase | Inhibitor | Tenalisib | RP 6530 | inhibit
Inhibitors RelatedMyricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | GDC0084 | Quercetin Dihydrate | Apilimod | LY294002 | Idelalisib
Related Compound LibrariesHighly Selective Inhibitor Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$32.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hills
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