Terbinafine Hydrochloride NEW
| Price | Get Latest Price |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | 20tons |
| Update Time: | 2024-04-05 |
Product Details
| Product Name: Terbinafine Hydrochloride | CAS No.: 78628-80-5 |
| EC-No.: 616-640-4 | Min. Order: 1kg |
| Purity: 99% | Supply Ability: 20tons |
| Release date: 2024/04/05 |
Terbinafine hydrochloride is an arylamine with broad-spectrum antifungal activity. It can specifically interfere with the early biosynthesis of fungal ergosterol, highly selective inhibition of fungal squalene epoxidase, so that the squalene epoxidation reaction during the formation of fungal cell membrane is blocked, thus achieving the effect of killing or inhibiting the fungus.
Terbinafine hydrochloride has a fungicidal effect on skin fungi and an inhibitory effect on Candida albicans. It is suitable for skin and nail infections caused by superficial fungi, such as ringworm, ringworm of the body, ringworm of the femur, ringworm of the feet, ringworm of the nail and Candida albicans infection of the skin caused by Trichophyton rubrum, Microsporum canis and Flocculus epidermidis.
| Item | Acceptance criteria | Result |
| Appearance | White or almost white powder | White powder |
| Solubility | Freely soluble in anhydrous ethanol and in methanol, slightly soluble in acetone, very slightly or slightly soluble in water. | Conforms |
| Identification | IR absorption spectrum of sample should be consistent with spectrum of standard | Consistent with spectrum of standard |
| It gives reaction (a) of chlorides using anhydrous ethanol as solvent | Forward reaction | |
| Related substances | B (Impurity B) W0. 15% | N.D |
| E (Impurity E) W0. 05% | N.D | |
| (Unspecified impurity) W0. 10% | 0.03% | |
| (Total impurities) W0. 3% | 0.09% | |
| Loss on drying | W0. 5% | 0.08% |
| Sulfated ash | W0. 1% | 0.04% |
| Residual solvents | (Isopropyl alcohol) W5000ppm | 94ppm |
| (Ethyl acetate) W5000ppm | 116ppm | |
| (Trichloromethane) W60ppm | 20ppm | |
| Assay | 99.0%-101.0% (Calculated on the dried basis) | 99.70% |
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