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Postion:Product Catalog >Biochemical Engineering>Nucleoside drugs>Nucleotides and their analogs>Uric acid sodium
Uric acid sodium
  • Uric acid sodium

Uric acid sodium NEW

Price $30 $40 $63
Package 100mg 200mg 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Uric acid sodium CAS No.: 1198-77-2
Purity: 99.92% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameUric acid sodium
DescriptionUric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, has an inhibitory effect on lipid peroxidation and is associated with the pathogenesis of gout joint disease and the formation of calcium oxalate stones.
In vitroUric acid, when administered at a concentration of 400 μM for 48 hours, offers protection to Caco-2 cells by preventing indomethacin-induced lipid peroxidation [2]. Furthermore, co-treatment of cells with indomethacin and uric acid sodium (200 μM indomethacin plus 400 μM uric acid; 24 hours) significantly reduces reactive oxygen species (ROS) levels compared to cells treated with indomethacin alone. Additionally, cell viability in Caco-2 cells exposed to both indomethacin and uric acid sodium (200 μM indomethacin plus 400 μM uric acid; 24 hours) is higher compared to cells treated solely with indomethacin. The protective effect of uric acid sodium on indomethacin-induced changes in intestinal cells is attributed to its antioxidant activity [2].
In vivoOral treatment of uric acid sodium at a dosage of 250 mg/kg has a beneficial effect on indomethacin-induced enteropathy. It ameliorates the enteropathy caused by indomethacin. Oral treatment of uric acid sodium leads to a reduction in ROS accumulation in the ileum in a mouse model of indomethacin-induced enteropathy [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 2.8 mg/mL (14.8 mM), when pH is adjusted to 4 with HCl. Sonication and heating to 60℃ are recommended.
KeywordsMonosodium urate | Uric acid sodium
Inhibitors RelatedSodium Thiocyanate | Imeglimin hydrochloride | Acetylcysteine | L-Ascorbic acid | α-Vitamin E | Glucosamine | D-(+)-Glucono-1,5-lactone | Lycopene | Coenzyme Q10 | Naringenin
Related Compound LibrariesBioactive Compound Library | Alkaloid Natural Product Library | Drug Repurposing Compound Library | Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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