ChemicalBook >>Nalidixic acid>>1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid(389-08-2)

1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid(389-08-2)

1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid(389-08-2)
Product IdentificationBack to Contents
【Product Name】

1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
【Synonyms】

1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
3-Carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one
Nalidic acid
Nevigramon
Specifin
Wintomylon
【CAS】

389-08-2
【Formula】

C12H12N2O3
【Molecular Weight】

232.24
【EINECS】

206-864-7
【RTECS】

QN2885000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

12,6446
【Beilstein/Gmelin】

750515
【Beilstein Reference】

5-25-07-00384
Physical and Chemical PropertiesBack to Contents
【Appearance】

Cream-colored powder.
【Solubility in water】

Very soluble
【Melting Point】

232 - 234
【Density】

1.41 g/cm3
【pKa/pKb】

1.20 (pKa)
【Partition Coefficient】

.43
【Usage】

Medication.
【Vapor Density】

8.01
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

May cause effects similar to those described for ingestion.
【Skin】

May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
【Eyes】

May cause painful sensitization to light. May cause visual abnormalities including: blurring, abnormal color vision, loss of sight.
【Ingestion】

May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May be harmful if swallowed. Exposure may cause hallucinations, convulsions, abnormal touch sensations and increased intracranial
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

Prolonged or repeated exposure may cause adverse reproductive effects.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
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