| Product Identification | Back to Contents | 【Product Name】
Levodopa | 【Synonyms】
(2S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid
3-(3,4-Dihydroxyphenyl)-L-alanine
L-DOPA | 【CAS】
59-92-7 | 【Formula】
C9H11NO4 | 【Molecular Weight】
197.19 | 【EINECS】
200-445-2 | 【RTECS】
AY5600000 | 【RTECS Class】
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
13,5485 | 【Beilstein/Gmelin】
2215169 | 【Beilstein Reference】
4-14-00-02492 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
White to beige powder. | 【Solubility in water】
1.6 g/L | 【Melting Point】
276-278 | 【Density】
1.515 g/cm3 | 【pKa/pKb】
2.32(at 25℃) (pKa) | 【Partition Coefficient】
-3.4 | 【Usage】
Used for the treatment of parkinsonian disorders and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. |
| First Aid Measures | Back to Contents | 【Ingestion】
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a cool, dry place. Keep container closed when not in use. Absorbs oxygen from the air and will darken upon exposure. Store protected from light. | 【Handling】
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Inhalation】
Causes respiratory tract irritation. | 【Skin】
Causes skin irritation. | 【Eyes】
Causes eye irritation. | 【Ingestion】
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause central nervous system effects such as psychosis, hallucinations, depression, visual changes and mental changes. May cause cardiac abnormalities. | 【EC Risk Phrase】
R 22 | 【EC Safety Phrase】
S 22 36/37 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | 【Exposure Effects】
Chronic ingestion may cause effects similar to those of acute ingestion. May cause reproductive and fetal effects. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. |
| Stability and Reactivity | Back to Contents | 【Stability】
Stable under normal temperatures and pressures. | 【Incompatibilities】
Strong oxidizing agents. | 【Decomposition】
Nitrogen oxides, carbon monoxide, carbon dioxide. |
|
| Company Name: |
Changxing Pharmaceutical Co., Ltd. |
| Tel: |
0572-6236833 13905823060 |
| Fax: |
0572-6236733 |
| WebSite: |
https://www.chemicalbook.com/ShowSupplierProductsList31068/0.htm |
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