| Product Identification | Back to Contents | 【Product Name】
Trimethoprim | 【Synonyms】
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
5-(3,4,5-Trimethoxyphenyl)methyl)-2,4-pyrimidinediamine
Monotrim
Proloprim
Trimpex
Uretrim | 【CAS】
738-70-5 | 【Formula】
C14H18N4O3 | 【Molecular Weight】
290.32 | 【EINECS】
212-006-2 | 【RTECS】
UV8225000 | 【RTECS Class】
Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
12,9840 | 【Beilstein/Gmelin】
625127 | 【Beilstein Reference】
5-25-13-00429 |
| First Aid Measures | Back to Contents | 【Ingestion】
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. | 【Inhalation】
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used. | 【Skin】
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. | 【Eyes】
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Inhalation】
Pyrimethamine produced apnea and tachycardia, as well as cyanosis, during the first two hours. | 【Skin】
Itching and rash may occur. | 【Ingestion】
Nausea and vomiting may occur. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. | 【Exposure Effects】
coma, seizures, and hyperpyrexia occurred in the above pyrimethamine cases, occurring as early as 45 minutes postingestion. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. | 【Fire Potential】
This material is probably combustible. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
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| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
| Company Name: |
TAIYUAN RHF CO.,LTD. |
| Tel: |
+86 351 7031519 |
| Fax: |
+86 351 7031519 |
| WebSite: |
www.rhfchem.com |
|