ChemicalBook >>Retinoic acid>>3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid(302-79-4)

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid(302-79-4)

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid(302-79-4)
Product IdentificationBack to Contents
【Product Name】

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
【Synonyms】

2,4,6,8-Nonatetraenoic acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
Atragen
Dermairol
trans-Retinoic acid
Vitamin A acid
【CAS】

302-79-4
【Formula】

C20H28O2
【Molecular Weight】

300.44
【EINECS】

206-129-0
【RTECS】

VH6475000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Primary Irritant
【Merck】

12,8333
【Beilstein/Gmelin】

2057223
【Beilstein Reference】

4-09-00-02387
Physical and Chemical PropertiesBack to Contents
【Appearance】

Yellow to light-orange crystalline powder.
【Solubility in water】

Insoluble
【Melting Point】

186 - 187
【Boiling Point】

277
【pKa/pKb】

4.79 (pKa)
【Partition Coefficient】

1.92
【Usage】

Medication.
First Aid MeasuresBack to Contents
【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
【Inhalation】

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from light.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light. Wash clothing before reuse.
Hazards IdentificationBack to Contents
【Inhalation】

Causes respiratory tract irritation. Can produce delayed pulmonary edema.
【Skin】

Causes skin irritation.
【Eyes】

Causes eye irritation. May cause chemical conjunctivitis.
【Ingestion】

May cause irritation of the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Effects may be delayed.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable at room temperature in closed containers under normal storage and handling conditions. May decompose when exposed to light.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
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