Gliclazide(21187-98-4)

Contents

Product Identification	Back to Contents
【Product Name】 Gliclazide
【Synonyms】 1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea 1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea
【CAS】 21187-98-4
【Formula】 C15H21N3O3S
【Molecular Weight】 323.42
【EINECS】 244-260-5
【RTECS】 YT4500000
【RTECS Class】 Drug; Reproductive Effector; Human Data
【Merck】 12,4448
【Beilstein/Gmelin】 1657836
【Beilstein Reference】 6-20

Physical and Chemical Properties	Back to Contents
【Solubility in water】 Slightly soluble
【Melting Point】 180 - 182
【Density】 1.319 g/cm3
【pKa/pKb】 7.82 (pKb)
【Usage】 Medicine used to help control blood sugar levels in people with type 2 diabetes.

First Aid Measures	Back to Contents
【Ingestion】 If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】 If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】 In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】 In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage	Back to Contents
【Storage】 Keep tightly closed.

Hazards Identification	Back to Contents
【Ingestion】 May be harmful if swallowed.
【Inhalation】 May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】 May cause skin irritation. May be harmful if absorbed through the skin.
【Eyes】 May cause eye irritation.
【Hazards】 Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection	Back to Contents
【Personal Protection】 Protective gloves. Chemical safety goggles.
【Respirators】 Wear dust mask.

Fire Fighting Measures	Back to Contents
【Fire Fighting】 Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures	Back to Contents
【Small spills/leaks】 Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity	Back to Contents
【Incompatibilities】 Acids, Bases, Strong oxidizing agents.
【Stability】 Stable at normal temperatures and pressures. Heat.
【Decomposition】 Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

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