| Product Identification | Back to Contents | 【Product Name】
6-Thioguanine | 【Synonyms】
2-Amino-3,7-dihydropurine-6-thione
2-Amino-6-mercaptopurine
2-Amino-6-purinethiol
2-Amino-9H-purine-6(1H)-thione
6-Thioguanine | 【CAS】
154-42-7 | 【Formula】
C5H5N5S | 【Molecular Weight】
167.19 | 【EINECS】
205-827-2 | 【RTECS】
UP0740000 | 【RTECS Class】
Drug; Mutagen; Reproductive Effector; Primary Irritant | 【Merck】
12,9473 | 【Beilstein/Gmelin】
157765 | 【Beilstein Reference】
4-26-00-03926 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Odorless or almost odorless pale yellow crystalline powder. | 【Solubility in water】
Soluble | 【Melting Point】
>360 | 【Boiling Point】
123 (29 torr) | 【pKa/pKb】
7.44 (pKa) | 【Partition Coefficient】
-.07 | 【Usage】
6-Thioguanine resistance is used as genetic markers for mutagen screening chinese hamster cells v-79 are described as convenient systems for detection of mutagens in vitro & in situ. |
| First Aid Measures | Back to Contents | 【Ingestion】
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. | 【Handling】
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Ingestion】
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. | 【Inhalation】
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. | 【Skin】
May cause skin irritation. | 【Eyes】
May cause eye irritation. | 【Hazards】
Contact with metals may evolve flammable hydrogen gas. | 【EC Risk Phrase】
R 25 63 | 【EC Safety Phrase】
S 22 36/37 45 | 【UN (DOT)】
2811 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. | 【Fire Potential】
This material is probably combustible. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. |
| Stability and Reactivity | Back to Contents | 【Incompatibilities】
Oxidizing agents. | 【Stability】
Stable under normal temperatures and pressures. | 【Decomposition】
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. | 【Combustion Products】
Fire may produce irritating, corrosive and/or toxic gases. |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Fax: |
86-21-50328109 |
| WebSite: |
https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Fax: |
021-67582001/03/05 |
| WebSite: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical |
| Tel: |
021-021-58432009 400-005-6266 |
| Fax: |
021-58436166 |
| WebSite: |
http://www.energy-chemical.com |
|