| Product Identification | Back to Contents | 【Product Name】
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid | 【Synonyms】
(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
17b-[1-Methyl-3-carboxypropyl]etiocholane-3a,7a,12a-triol
5b-Cholanic acid-3a,7a,12a-triol
5b-Cholic acid
Cholan-24-oic acid, 3,7,12-trihydroxy-, (3a,5b,7a,12a)- | 【CAS】
81-25-4 | 【Formula】
C24H40O5 | 【Molecular Weight】
408.57 | 【EINECS】
201-337-8 | 【RTECS】
FZ9350000 | 【RTECS Class】
Mutagen | 【Merck】
13,2223 | 【Beilstein/Gmelin】
2822009 | 【Beilstein Reference】
4-10-00-02072 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
White. | 【Solubility in water】
Insoluble | 【Melting Point】
199 | 【Boiling Point】
545 | 【pKa/pKb】
4.76 (pKa) | 【Partition Coefficient】
3.04 | 【Usage】
One of two major bile acids produced by the liver where it is synthesized from cholesterol. |
| First Aid Measures | Back to Contents | 【Ingestion】
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. | 【Inhalation】
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. | 【Skin】
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a cool, dry place. Keep container closed when not in use. | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Ingestion】
The toxicological properties of this substance have not been fully investigated. | 【Inhalation】
The toxicological properties of this substance have not been fully investigated. | 【Skin】
No information regarding skin irritation and other potential effects was found. | 【Eyes】
May cause eye irritation. No information regarding eye irritation and other potential effects was found. | 【EC Safety Phrase】
S 22 24/25 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. |
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