ChemicalBook >>Danazol>>17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole(17230-88-5)

17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole(17230-88-5)

17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole(17230-88-5)
Product IdentificationBack to Contents
【Product Name】

17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole
【Synonyms】

17b-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole
Danazol
Danocrine
Danol
Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol, (17a)-
【CAS】

17230-88-5
【Formula】

C22H27NO2
【Molecular Weight】

337.46
【EINECS】

241-270-1
【RTECS】

TU4157070
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone
【Merck】

12,2875
【Beilstein/Gmelin】

1088173
【Beilstein Reference】

5-27
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【Melting Point】

225
【Boiling Point】

478
【Vapor Pressure】

6E-10 (25 C)
【pKa/pKb】

13.10 (pKa)
【Heat Of Vaporization】

78.2 kJ/mol
【Usage】

Weak androgen and anterior pituitary suppressant.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】

Government approved respirator.
【Exposure Effects】

Harmful. Possible risk of harm to the unborn child. Harmful by inhalation, in contact with skin and if swallowed. Calif. Prop. 65 reproductive hazard. Target organ(s): Female reproductive system. Pituitary.
Fire Fighting MeasuresBack to Contents
【Flash Point】

243
【Fire Fighting】

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Hazards IdentificationBack to Contents
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

20/21/22 63
【EC Safety Phrase】

22 36
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