阿地米屈是壬二酸的合成酰胺衍生物,具有对称的化学结构。它被归类为一个己二酰二胺,类似于十六酰胺乙醇。Adelmidrol发挥了重要的抗炎作用,这些作用部分依赖于PPARγ。阿地米屈可减少NF-κB转录和COX-2表达。
AdelMitrol is a synthetic amide derivative of azelaic acid with a symmetric chemical structure. It is classified as an adipoyl diamine, similar to hexadecanamide ethanolamine.Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ. Adelmidrol reduces NF-κB translocation, and COX-2 expression.
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