8- [4-（1-氨基环丁基）苯基] -9-苯基-1,2,4-三唑并[3,4-f] [1,6]萘啶-3（2H）-二盐酸盐

中文名称

8- [4-（1-氨基环丁基）苯基] -9-苯基-1,2,4-三唑并[3,4-f] [1,6]萘啶-3（2H）-二盐酸盐

英文名字

8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, dihydrochloride

供应商

开曼生物

产品货号

11593-5

产品报价

￥1/5mg

产品说明书

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产品新闻

背景资料

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKB

产品描述

An orally active, allosteric Akt inhibitor (IC50s = 5, 12, and 65 nM for Akt1, 2, and 3, respectively); inhibits cell proliferation of human cancer cell lines synergistically in combination with other topoisomerase inhibitors, antimetabolites, antimicrotubule agents, DNA cross-linkers or growth factor inhibitors

保存建议

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