中文名称
DeepBlueC™;6-苯基-2,8-双(苯甲基)-咪唑并[1,2-a]吡嗪-3(7H)-one
英文名字
DeepBlueC™; 6-phenyl-2,8-bis(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one
供应商
开曼生物
产品货号
16157-1
产品报价
¥2186.8/1mg
产品说明书
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购买方式
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产品新闻
背景资料
Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins.{22804} The oxidation of coelenterazine to coelenteramide is accompanied by emission of blue light (emission maximum = 460-470 nm). Luciferase-mediated oxidation of coelenterazine or a derivative is used as an energy donor, typically to a form of green fluorescent protein (GFP), in bioluminescent resonance energy transfer (BRET) studies.{26295,26296,26290} Coelenterazine 400a is a bisdeoxy derivative of coelenterazine that produces an emission peak near 400 nm following conversion by Renilla luciferase (Rluc).{26297,26291} It is used in BRET2 protocols, whereas coelenterazine h, which has a 475 nm Rluc emission peak, is used in BRET1 protocols.{26296} The emission peak of coelenterazine 400a is commonly paired with class 1 and 3 GFPs, including GFP2 and GFP10.{26296,26291} BRET2 assays are commonly used in evaluating protein-protein interactions, including those involved in G protein-coupled receptor signaling.{26297,26291,26294}
产品描述
A bisdeoxy derivative of coelenterazine that produces an emission peak near 400 nm following conversion by Renilla luciferase; commonly used in BRET2 protocols to evaluate protein-protein interactions
保存建议
建议您在收到开曼生物品牌的Coelenterazine 400a (1 mg)产品后置于-20度保存,产品有效期为730天.
其他
开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.
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