肝微粒体是体外研究一个化合物的代谢(酶抑制,清除率和代谢鉴定)以及药物-药物相互作用的主要工具。通常根据特定细胞色素酶的活性水平来选择微粒体。 齐氏生物提供的肝细胞微粒体,每批产品都经过严格的制备、检测,确保批次间稳定性,然后于冻存管包装,10 mg/管;-80℃保存,干冰运输。 用途:ADME及药代动力学检测试验 种属:人/大鼠/小鼠/兔/狗/猪/猴 /牛 规格:0.5ml 20mg/ml 运输:冻存管,干冰运输。 微粒体产品被SCI论文引用(部分):1.Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolitesQ Liu, Y Wang, CX Xiao, W Wu, X Liu - Food & function, 2015 - pubs.rsc.org… 11–14 Moreover, chicoric acid has showed anti-inflammatory, anti-bacterial, anti-HIVactivities, hypoglycemic and hepatocyte protective properties … Rat liver microsomeswere obtained from CHI Scientific, Inc. (Massachusetts, USA) 2.Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapyC Huang, J Zheng, D Ma, N Liu, C Zhu, J Li… - Journal of Materials …, 2018 - pubs.rsc.org… Rat liver microsomes were purchased from CHI Scientific (Jiangsu China … under hypoxic conditions(red curve); DDS in the presence of inactive rat liver microsomes and NADPH … 0 represent thefluorescence intensity of TAMRA after and before rat liver microsome addition under …附:产品介绍
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