Name: Sydowinin B
CAS#: 58450-00-3
Chemical Formula: C16H12O7
Exact Mass: 316.0583
Molecular Weight: 316.265
Elemental Analysis: C, 60.76; H, 3.82; O, 35.41
Description: Sydowinin B is a xanthone polyketide that has been found in A. sydowii and has immunosuppressant activity. It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 µg/ml, respectively). Sydowinin B inhibits superoxide generation in, and elastase release from, isolated human neutrophils induced by cytochalasin B and fMLP with IC50 values of 21.2 and 12.62 µM, respectively.
IUPAC/Chemical Name: 9H-Xanthene-1-carboxylic acid, 2,8-dihydroxy-6-(hydroxymethyl)-9-oxo-, methyl ester
InChi Key: SSBSKLSIZKVBFF-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H12O7/c1-22-16(21)13-8(18)2-3-10-14(13)15(20)12-9(19)4-7(6-17)5-11(12)23-10/h2-5,17-19H,6H2,1H3
SMILES Code: O=C(C1=C(O)C=CC(OC2=C3C(O)=CC(CO)=C2)=C1C3=O)OC
Appearance: Solid powder
关键字： 58450-00-3;Sydowinin B;
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