Name: SIB-1893
CAS#: 7370-21-0
Chemical Formula: C14H13N
Exact Mass: 195.1048
Molecular Weight: 195.27
Elemental Analysis: C, 86.12; H, 6.71; N, 7.17
Description: SIB-1893 is a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. It positive allosteric modulator at mGlu4 receptors.
IUPAC/Chemical Name: 2-Methyl-6-(2-phenylethenyl)pyridine
InChi Key: SISOFUCTXZKSOQ-ZHACJKMWSA-N
InChi Code: InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
SMILES Code: CC1=NC(/C=C/C2=CC=CC=C2)=CC=C1
Appearance: Solid powder
关键字： 7370-21-0;SIB-1893;
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