三仲丁基硼氢化锂

性质 Properties

本品是一个强还原剂，具有高度立体选择性。闪点为-17℃。

This product is a strong reducing agent and it has very high stereoselectivity. Flash point :-17℃.

用途 Usage

三仲丁基硼氢化锂是一种高选择性的强还原剂。用于酮的非对称选择还原得到醇，也可用于烯酮的1,4共轭加成还原得到酮或醇，用于选择性还原环外丙烯腈衍生物的共轭双键和碘化物。对于二酯、脱卤单环嘧啶、重排5-三甲基甲硅烷基蒂巴因和脱保护的N-甲氧羰基的阿片样物质取代N-非阿片类反应中，它也是一种有效的去对称内消旋试剂。在低温条件下可有效还原共轭羰基化合物。

This product is a high stereoselective reducing agent. It has been used for the diastereoselective reduction of the ketones to give the alcohol. It can be also used for selective 1,4- addition of the enones to provide ketones or alcohols. It is used for selective reduction of the conjugated double bonds of cyclic acrylonitrile derivatives and iodide. It was also found to be an efficient reagent for the mesomerize reaction of diesters, dehalogenation of monocyclic Pyrimidine, rearrangement of 5-trimethylsilyl Thebaine, and deprotection of N-carbomethoxy-substituted opioids to N-noropioids. At low temperatures, it can effectively reduce conjugated carbonyl compounds.