Description: alphaSYN-IN-NAB2 is an inhibitor of α-synuclein mutations. It acts by reversing the α-synuclein-induced pathological phenotype in Parkinson's disease cortical neurons and promoting E3 ubiquitin ligase Rsp5/Nedd4-dependent endosomal transport.
Name:alphaSYN-IN-NAB2
CAS#: 1504588-00-4
Chemical Formula: C23H20ClN3O
Exact Mass: 389.1295
Molecular Weight: 389.88
Elemental Analysis: C, 70.86; H, 5.17; Cl, 9.09; N, 10.78; O, 4.10
Synonym: alphaSYN-IN-NAB2; alphaSYN IN NAB2; alphaSYNINNAB2; alphaSYN inhibitor NAB2; alphaSYN inhibitor-NAB2; NAB2; α-Synuclein inhibitor NAB2; αSyn-reversor-NAB2; Rsp5/Nedd4 actovator NAB2; NAB2; NAB 2; NAB-2;
IUPAC/Chemical Name: N-[(2-Chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-benzimidazole-5-carboxamide
InChi Key: CZSLEMCYYGEGKP-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H20ClN3O/c1-15-7-8-16(2)22(11-15)27-14-26-20-12-17(9-10-21(20)27)23(28)25-13-18-5-3-4-6-19(18)24/h3-12,14H,13H2,1-2H3,(H,25,28)
SMILES Code: O=C(C1=CC=C2C(N=CN2C3=CC(C)=CC=C3C)=C1)NCC4=CC=CC=C4Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
关键字： alphaSYN-IN-NAB2;1504588-00-4;
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