Name: Amifampridine
CAS#: 54-96-6 (free base)
Chemical Formula: C5H7N3
Exact Mass: 109.064
Molecular Weight: 109.132
Elemental Analysis: C, 55.03; H, 6.47; N, 38.50
Description: Amifampridine is used as a drug, predominantly in the treatment of a number of rare muscle diseases. The phosphate salt of amifampridine is a more stable formulation that does not require refrigeration. In the United States, amifampridine is under investigation for the treatment of Lambert-Eaton myasthenic syndrome (LEMS). Amifampridine is also used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor.
Synonym: 3,6-DAP; BRN-0110232; BRN 0110232; BRN0110232; NSC 521760; SC10; Amifampridine; Firdapse.
IUPAC/Chemical Name: 3,4-Diaminopyridine
InChi Key: OYTKINVCDFNREN-UHFFFAOYSA-N
InChi Code: InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
SMILES Code: NC1=C(N)C=NC=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
关键字： Amifampridine; 54-96-6 (free base);
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