中文名称
英文名字
Ceramide trihexosides; Gb3
供应商
Matreya
产品货号
1067-1
背景资料
Ceramide trihexoside (CTH) is a glycosphingolipid found mostly in mammalian cell membranes. It is involved in cellular signaling and has been identified as a receptor for various toxins including shiga toxins and shiga-like toxins.1 Some toxins, such as veratoxins from Escherichia coli, require specific fatty acids on the ceramide portion of CTH to show affinity in binding. An accumulation of CTH in the cellular membranes due to a lack of alpha-galactosidase to convert it into lactosyl ceramide results in Fabry disease.2 This product can be used as an excellent standard for the identification of CTH in Fabry disease by HPLC3 and mass spectrometry.4 An inability to convert CTH to globoside due to mutations in the gene sequence leads to the Pk blood group phenotype. It appears that under certain conditions CTH can enhance anticoagulant activity. CTH has also been studied as a tool to investigate lymphocyte activation.5
产品描述
Gb3|Globotriaosylceramide|GTH
产品形式
该神经酰胺三己糖; Gb3产品为固体形式
保存建议
对于本产品,我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后,我们建议在-20℃温度下冷冻保存,溶解使用说明请参考本品说明书。
湖北艾普蒂生物工程有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!