中文名称
英文名字
Urine microRNA Purification Kit (25)
供应商
Norgen Biotek
产品货号
NGB-29000
背景资料
尿液microRNA纯化试剂盒(提取试剂盒)产品的背景资料详情查看Norgen Biotek品牌提供的产品说明书
产品描述
Norgen’s Urine microRNA Purification Kit provides a rapid method for the isolation and purification of small RNA molecules (< 200 nt) from urine samples. These small RNAs include regulatory RNA molecules such as microRNA (miRNA) as well as tRNA and 5S rRNA. Small RNA molecules are often studied due to their ability to regulate gene expression. Typically miRNAs are 20-25 nucleotides long, and regulate gene expression by binding to mRNA molecules and affecting their stability or translation. Several recent studies have shown that miRNA regulates cell growth and apoptosis. Furthermore, clinical and experimental analyses suggested that miRNAs may function as a novel class of oncogenes or tumor suppressor genes. MicroRNA expression profiles of different tumor types, relative to their normal tissues, have recently been shown to provide phenotypic signatures for particular cancer types. Unique patterns of aberrant miRNA expression may serve as molecular biomarkers for tumor diagnosis, prognosis of disease specific outcomes, and prediction of therapeutic responses.
产品特点
Isolate high quality total RNA and all sizes of circulating and exosomal RNA, including microRNA; Small urine input ranging from as low as 0.5 mL to 1 mL; No phenol extractions; Very sensitive and linear down to a few cells without the need for carrier RNA; Bind and elute all RNA irrespective of size or GC content, without bias; Rapid and convenient spin-column protocol.
保存建议
溶液密封室温保存,未开封至少保存1年。
其他
Norgen Biotek成立于1998年,公司总部位于加拿大,是一家著名全球化生物技术公司,基于专利的碳化硅膜纯化技术和无苯酚专利配方,生产高品质的核酸和蛋白质纯化及富集产品用于研究和诊断。Norgen Biotek 在2003年获得加拿大国家研究委员会颁发的科技创新奖,是一家致力于样品制备并获得ISO 9001(产品质量)、ISO 13485(产品可用于商业化的医疗设备,包括用于体外诊断领域)和ISO 15189(可用于临床检测机分子诊断领域的研发能力)认证的生物科技公司。 目前该公司的产品多达700余种,提供一流的样品制备试剂盒,应用于基因组和蛋白组等不同的领域。其产品主要覆盖包括各种标本类型的DNA,RNA和蛋白质的纯化富集,从活检样本(包括尿液,血浆,血清和血液)中纯化RNA和DNA,全系列的PCR试剂、缓冲液、分子量ladder和塑料过滤装置。
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