N'-[4'-（二甲基氨基）[1，-1'-联苯] -3-3-基] -N，N-二甲基脲

中文名称

N'-[4'-（二甲基氨基）[1，-1'-联苯] -3-3-基] -N，N-二甲基脲

英文名字

N’-[4’-(dimethylamino)[1,1’-biphenyl]-3-yl]-N,N-dimethyl-urea

供应商

开曼生物

产品货号

15284-10

背景资料

Adipose triglyceride lipase (ATGL or PNPLA2) catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets, generating diacylglyerol.{21269,21272} Atglistatin is a potent, selective, and competitive inhibitor of ATGL (IC50 = 0.7 μM).{24582} It does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases.{24582} Atglistatin blocks lipolysis by ATGL in vitro, in white adipose tissue organ cultures, and in vivo.{24582} It does not affect lipolysis in ATGL knockout mice.{24582}

产品描述

A potent, selective, and competitive inhibitor of ATGL (IC50 = 0.7 μM); does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases; blocks lipolysis by ATGL in vitro, in white adipose tissue organ cultures, and in vivo

保存建议

建议您在收到开曼生物品牌的Atglistatin (10 mg)产品后置于-20度保存，产品有效期为730天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.