产品属性:
产品名称
规格
CAS号
型号
(±)-BI-D
10mM 2mg 5mg 10mg 50mg 100mg 200mg 500mg
1416258-16-6
EY-Y016333
Cas No.1416258-16-6
别名 N/A
化学名 N/A
分子式 C25H27NO4
分子量 405.49
溶解度 DMSO: ≥ 100 mg/mL (246.62 mM)
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.IC50 value: 2.4-2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) [1]Target: integrase inhibitorin vitro: Approximately 2.4-2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160-200 nM, in Psip1 and double-KO cells [1].
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