产品属性:
产品名称 | 规格 | CAS号 | 型号 |
13(S)-HODE-d4 | 100μg 50μg 25μg | 139408-39-2 | EY-Y016449 |
Cas No.139408-39-2
别名 N/A
化学名 N/A
分子式 C18H28D4O3
![13(S)-HODE-d4.jpg 13(S)-HODE-d4.jpg](/SupplyImg/2022-11-22/6380470427205540438649415.jpg)
分子量 300.5
溶解度 DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
13(S)-HODE-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of 13(S)-HODE by GC- or LC-mass spectrometry. 13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 μM,1,2 and down regulates the expression of the IRGpIIb/IIIa receptor.3
1.Buchanan, M.R., Haas, T.A., Lagarde, M., et al.13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOXThe Journal of Biological Chemisty26016056-16059(1985) 2.Honn, K.V., Nelson, K.K., Renaud, C., et al.Fatty acid modulation of tumor cell adhesion to microvessel endothelium and experimental metastasisProstaglandins44(5)413-429(1992) 3.Grossi, I.M., Fitzgerald, L.A., Umbarger, L.A., et al.Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acidCancer Res.49(4)1029-1037(1989)
关键字: 139408-39-2;C18H28D4O3;13(S)-HODE-d4;
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