产品属性:
产品名称 | 规格 | CAS号 | 型号 |
14,15-dehydro Leukotriene B4 | 25μg 50μg 100μg | 114616-11-4 | EY-Y016455 |
Cas No.114616-11-4
别名 N/A
化学名 N/A
分子式 C20H30O4
![14,15-dehydro Leukotriene B4.jpg 14,15-dehydro Leukotriene B4.jpg](/SupplyImg/2022-11-22/6380470480204871827292613.jpg)
分子量 334.5
溶解度 DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): >1 mg/ml
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 μM.
关键字: 114616-11-4;C20H30O4;14,15-dehydro Leukot;
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