产品属性:
产品名称
规格
CAS号
型号
3'-Hydroxy Repaglinide
5mg
874908-14-2
EY-Y016545
Cas No.874908-14-2
别名 N/A
化学名 N/A
分子式 C27H36N2O5
分子量 468.59
溶解度 Soluble in DMSO
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: 3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].
[1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268. [2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.
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