产品属性:
产品名称 | 规格 | CAS号 | 型号 |
3-Indolepropionic acid | 1g | 830-96-6 | EY-Y0163511 |
Cas No.830-96-6
别名 N/A
化学名 N/A
分子式 C11H11NO2
分子量 189.21
溶解度 DMSO: ≥ 100 mg/mL (528.51 mM); H2O: 1 mg/mL (5.29 mM; ultrasonic and warming and heat to 80°C)
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease.
3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease[1]. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds[2]. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function[3].
[1]. Wikoff WR, et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3698-703. [2]. Reiter RJ, et al. Reactive oxygen intermediates, molecular damage, and aging. Relation to melatonin. Ann N Y Acad Sci. 1998 Nov 20;854:410-24. [3]. de Mello VDet al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Sci Rep. 2017 Apr 11;7:46337. doi: 10.1038/srep46337.
关键字: 830-96-6;C11H11NO2;3-Indolepropionic ac;
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