产品属性:
产品名称 | 规格 | CAS号 | 型号 |
5-Methoxyindole-3-acetic acid | 500mg | 3471-31-6 | EY-Y0163650 |
Cas No.3471-31-6
别名 N/A
化学名 N/A
分子式 C11H11NO3
分子量 205.2
溶解度 DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 10 mg/ml
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
5-Methoxyindole-3-acetic acid (5-MIAA) is a methoxyindole that is synthesized in rat pineal gland, retina, and harderian gland.1 Following conversion to a peroxyl radical by horseradish peroxidase (HRP), 5-MIAA increases the rate of formation of thiobarbituric acid reactive substances (TBARS) in liposomes and is cytotoxic to V79 hamster cells.2,3 In vivo, 5-MIAA (100 and 200 μg/animal) prolongs the estrous cycle and increases diestrous smears, uterine weight, the number of uterine follicles, and plasma levels of 17β-estradiol in female rats.1
|1. Ocal-Irez, T., Durmus, G., Sekerkiran, Y., et al. Effect of a pineal indolamine, 5-methoxyindole-3-acetic acid, on the estrous cycle and reproductive organs of female wistar albino rats. Brain Res. 493(1), 1-7 (1989).|2. Candeias, L.P., Folkes, L.K., Porssa, M., et al. Enhancement of lipid peroxidation by indole-3-acetic acid and derivatives: Substituent effects. Free Radic. Res. 23(5), 403-418 (1995).|3. Folkes, L.K., Candeias, L.P., and Wardman, P. Toward targeted "oxidation therapy" of cancer: Peroxidase-catalysed cytotoxicity of indole-3-acetic acids. Int. J. Radiat. Oncol. Biol. Phys. 42(4), 917-920 (1998).
关键字: 3471-31-6;C11H11NO3;5-Methoxyindole-3-ac;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业,公司自成立以来,秉承""全心全意服务于科研工作者""的企业理念,立足生物科技领域,运用生物技术和科研试剂,发展现代生物科技,为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品,服务生物科技领域的科学研究人员。
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