产品属性:
产品名称
规格
CAS号
型号
8-hydroxy Efavirenz
1mg
205754-33-2
EY-Y0163689
Cas No.205754-33-2
别名 N/A
化学名 N/A
分子式 C14H9ClF3NO3
分子量 331.7
溶解度 Acetonitrile: soluble,DMSO: soluble,Methanol: soluble
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.
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