产品属性：
产品名称 | 规格 | CAS号 | 型号 |
Antipain (hydrochloride) | 5mg 10mg 25mg | 37682-72-7 | EY-Y0163834 |
Cas No.37682-72-7
别名 N/A
化学名 N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide, dihydrochloride
分子式 C27H44N10O6 2HCl
分子量 677.6
溶解度 Soluble in ethanol, DMSO, also soluble in water
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Antipain is a protease inhibitor originally isolated from actinomycetes.[1] It inhibits thrombokinase, plasmin, trypsin, and papain in vitro (IC50s = 20, 93, 0.26, and 0.16 μg/ml, respectively). Antipain (6-600 μg/ml) inhibits the morphological transformation of and increases frequency of chromosomal aberrations in Syrian hamster embryo cells induced by N-methyl-N'-nitro-N-nitroso-guanidine (MNNG).[2] In vivo, antipain (25-100 mg/kg) suppresses urethan-induced formation of cleft palates and cleft lips in mice.[3]
Reference:
[1]. Suda, H., Aoyagi, T., Hamada, M., et al. Antipain, a new protease inhibitor isolated from actinomycetes. J. Antibiot. (Tokyo) 25(4), 263-266 (1972).
[2]. DiPaolo, J.A., Amsbaugh, S.C., and Popescu, N.C. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation and increases chromosomal aberrations. Proc. Natl. Acad. Sci. U.S.A. 77(11), 6649-6653 (1980).
[3]. Nomura, T., Enomoto, T., Shibata, K., et al. Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice. Cancer Res. 43(11), 5156-5162 (1983).
关键字： 37682-72-7;C27H44N10O6 ? 2HCl;Antipain (hydrochlor;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业，公司自成立以来，秉承""全心全意服务于科研工作者""的企业理念，立足生物科技领域，运用生物技术和科研试剂，发展现代生物科技，为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品，服务生物科技领域的科学研究人员。
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