产品属性:
产品名称
规格
CAS号
型号
AZD5904
25mg 5mg 10mg 50mg 100mg
618913-30-7
EY-Y0163900
Cas No.618913-30-7
别名 N/A
化学名 N/A
分子式 C10H12N4O2S
分子量 252.29
溶解度 DMSO : 125 mg/mL (495.46 mM)
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.
AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. In isolated human neutrophils, 1 μM AZD5904 inhibits PMA stimulated HOCl by >90%[1].
[1]. Myeloperoxidase (MPO) inhibitor.
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