产品属性:
产品名称
规格
CAS号
型号
IDH1 Inhibitor 3
100mg 250mg 500mg
2171081-24-4
EY-Y0164627
Cas No.2171081-24-4
别名 N/A
化学名 N/A
分子式 C31H25F4N5O3
分子量 591.56
溶解度 Soluble in DMSO
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1]. IC50: 45 nM (IDH1R132H)[1].
[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.
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