产品属性:
产品名称
规格
CAS号
型号
JG-98
5mg 10mg 50mg
1456551-16-8
EY-Y0164638
Cas No.1456551-16-8
别名 N/A
化学名 N/A
分子式 C24H21Cl2N3OS3
分子量 534.54
溶解度 DMSO : 5 mg/mL (9.35 mM)
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: JG-98 is a heat shock protein 70 (Hsp70) Inhibitor with anti-cancer activities[1][2]. Heat shock protein 70[1]
JG-98 inhibits the breast cancer cell lines MDA-MB-231 and MCF-7 with EC50 values of 0.4 and 0.7 μM, respectively[1].
[1]. Yaglom JA, et al. Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and findingsynergistic drug combinations. Sci Rep. 2018 Feb 14;8(1):3010.
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