产品属性:
产品名称 | 规格 | CAS号 | 型号 |
Decylubiquinone | 5mg 10mg 25mg 50mg | 55486-00-5 | EY-Y0164663 |
Cas No.55486-00-5
别名 N/A
化学名 2-decyl-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
分子式 C19H30O4
分子量 322.4
溶解度 10mg/mL in DMSO, or in DMF
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Decylubiquinone is an analog of ubiquinone . It blocks reactive oxygen species production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition. [1] Decylubiquinone inhibited opening of the mitochondrial permeability transition pore in response to calcium overload in rat liver mitochondria in different cell lines at concentrations between 50-100 µM.[2]
Reference:
[1]. Armstrong, J.S., Whiteman, M., Rose, P., et al. The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: Role of mitochondrial complex III. J. Biol. Chem. 278(49), 49079-49084 (2003).
[2]. Devun, F., Walter, L., Belliere, J., et al. Ubiquinone analogs: A mitochondrial permeability transition pore-dependent pathway to selective cell death. PLoS One 5(7), (2010).
关键字: 55486-00-5;C19H30O4;Decylubiquinone;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业,公司自成立以来,秉承""全心全意服务于科研工作者""的企业理念,立足生物科技领域,运用生物技术和科研试剂,发展现代生物科技,为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品,服务生物科技领域的科学研究人员。
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