产品属性:
产品名称
规格
CAS号
型号
Desethyl KBT-3022
1mg 5mg 10mg 20mg
101001-72-3
EY-Y0164673
Cas No.101001-72-3
别名 N/A
化学名 N/A
分子式 C23H20N2O4S
分子量 420.48
溶解度 Soluble in DMSO
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: Desethyl KBT-3022 is the main active metabolite of the new antiplatelet agent, KBT-3022.
Pretreatment with desethyl KBT-3022 0.1, 0.3 and 1 mg/kg, i.v. prolongs the time required to achieve thrombotic occlusion in the femoral artery and inhibits collagen-induced platelet aggregation in whole blood ex vivo, each in a dose-dependent manner. Desethyl KBT-3022 inhibits the thrombin-induced aggregation of washed platelets in a concentration-dependent manner 1-40 μM[1].
[1]. Shimazawa M, et al. Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022. Eur J Pharmacol. 1997 Jun 11;328(2-3):183-9.
上海一研生物科技有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!