产品属性:
产品名称 | 规格 | CAS号 | 型号 |
Celecoxib Carboxylic Acid | 5mg 10mg 50mg 25mg mg | 170571-01-4 | EY-Y0164854 |
Cas No.170571-01-4
别名 N/A
化学名 N/A
分子式 C17H12F3N3O4S
![Celecoxib Carboxylic Acid.jpg Celecoxib Carboxylic Acid.jpg](/SupplyImg/2022-11-28/6380523709867614578486291.jpg)
分子量 411.4
溶解度 DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:6): 0.12 mg/ml,PBS (pH 7.2): slightly soluble
储存条件 Store at-20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
Celecoxib carboxylic acid is an inactive metabolite of the COX-2 inhibitor celecoxib .1,2 It is formed from celecoxib primarily by the cytochrome P450 (CYP) isoform CYP2C9.
1.Liu, H., Huang, X., Shen, J., et al.Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: Molecular docking and 3D QSAR analysesJ. Med. Chem.45(22)4816-4827(2002) 2.Kim, S.-H., Kim, D.-H., Byeon, J.-Y., et al.Effects of CYP2C9 genetic polymorphisms on the pharmacokinetics of celecoxib and its carboxylic acid metaboliteArch. Pharm. Res.40(3)382-390(2017)
关键字: 170571-01-4;C17H12F3N3O4S;Celecoxib Carboxylic;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业,公司自成立以来,秉承""全心全意服务于科研工作者""的企业理念,立足生物科技领域,运用生物技术和科研试剂,发展现代生物科技,为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品,服务生物科技领域的科学研究人员。
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