137319-34-7Dehydroeffusol

产品属性：

Cas No.137319-34-7

别名 N/A

化学名 N/A

分子式 C17H14O2

分子量 250.29

溶解度 Soluble in DMSO

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity[1][2].

Dehydroeffusol suppresses the expression of vasculogenic mimicry key gene VE-cadherin[2].Dehydroeffusol decreases the MMP2 expression and activity in gastric cancer cells[2].

[1]. Zhang B, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18. [2]. Liu W, et al. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity. Toxicol Appl Pharmacol. 2015 Sep 1;287(2):98-110.