产品属性:
产品名称
规格
CAS号
型号
CAY10406
1mg 5mg 10mg 100mg
2108603-03-6
EY-Y0165513
Cas No.2108603-03-6
别名 N/A
化学名 N/A
分子式 C27H23F3N2O5S
分子量 544.5
溶解度 DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:2): 0.5 mg/ml,DMSO: 10 mg/ml,Ethanol: .05 mg/ml
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are 'effector caspases' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.
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