应用
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
其他说明
Technology Spotlight: Trifuctional Probe Building BlocksA library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpSSynthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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