别名
(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide,(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide
应用
(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist: in mice to test the activity of the serotonin receptorto test its effect on zebrafish melanocyte migration and survival to stimulate hippocampal neurons
生化/生理作用
(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation. (R)-(+)-8-Hydroxy-DPAT is a full 5-HT1A serotonin receptor agonist; active enantiomer of (±)-8-hydroxy-DPAT.
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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