Product Name:AUNP-12
CAS No.:1353563-85-5
Synonyms:抑制剂多肽AUNP-12
Catalog No.:1353563-85-5
Brand:HongTide
Description:AUNP-12是一种新型的免疫检查点调节剂,是PD-1信号通路的抑制剂多肽,序列中含有29个氨基酸,肽链中具有分支结构,赖氨酸侧链接上一个7个氨基酸的支链。在表达hPDL2的HEK293细胞中,对淋巴细胞增殖和效应功能方面对PD-L1和PD-L2表现出等效的拮抗作用。EC50为0.72 nM;在表达hPDL1的MDA-MB231细胞中,PBMC增殖试验中,EC50为0.41 nM。
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code)
EKIQAKPALQTVRFK(FSESTNS)FSESTNS
Sequence(3-letter code)
H-Glu-Lys-Ile-Gln-Ala-Lys-Pro-Ala-Leu-Gln-Thr-Val-Arg-Phe-Lys(Phe-Ser-Glu-Ser-Thr-Asn-Ser)-Phe-Ser-Glu
-Ser-Thr-Asn-Ser-OH
Peptide Structure
Molecular Formula
C142H225N39O49
Molecular Weight
3262.58
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
联系商家时请提及chemicalbook,有助于交易顺利完成!
鸿肽生物