Product Name:Pardaxin
CAS No.:67995-63-5
Synonyms:豹鳎毒素
Catalog No.:218P008
Brand:HongTide(上海鸿肽)
Description:豹鳎毒素(pardaxin)是一种具有α-螺旋结构的多肽,包含33个氨基酸,因最早在石纹豹鳎体内被发现而得名。豹鳎背鳍、腹鳍和臀鳍基部有超过两百个毒腺由小孔通向体外,豹鳎毒素就从这里产生并被分泌到体表黏液中去,这种毒素能够破坏细胞中的磷脂双分子层,改变细胞的渗透性,引起细胞溶解释放内容物,并像表面活性剂一样降低细胞表面的张力。Pardaxin是一种抗菌、凋亡和神经毒性离子载体多肽。能在脂质膜上形成孔,同时能诱导半胱天冬酶依赖性和ROS介导的细胞凋亡;刺激花生四烯酸(Asc 916)和类花生酸的钙非依赖性PLA2释放,在体内非常活跃。
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code)
GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE
Sequence(3-letter code)
H-Gly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Gly-Gln-Glu-OH
Peptide Structure
Molecular Formula
C154H248N36O45
Molecular Weight
3323.88
订购联系方式:
上海鸿肽生物科技有限公司
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QQ: 3259098395
邮箱:sales1@hongtide.com
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鸿肽生物