Product Name：c(RGDfV)
CAS No.：137813-35-5
Synonyms：细胞粘附抑制剂多肽cyclo (Arg-Gly-Asp-d-Phe-Val)
Catalog No.：143P24
Brand：HongTide（上海鸿肽）
Description：c(RGDfV)是一种有效的细胞粘附抑制剂，是由5个氨基酸组成的环状多肽，可抑制肿瘤细胞对层粘连蛋白和玻连蛋白底物的粘附。大鼠体内的研究提供了其在改善缺血性急性肾功能衰竭中的效用的个证据。c(RGDfV)还通过阻止细胞间粘附来抑制肾小管阻塞，还有实验表明环肽c(RGDfV)还可用于预防视网膜新生血管形成；其次，c(RGDfV)还能与avb3受体结合。
c(RGDfV) is an effective cell adhesion inhibitor, a cyclic peptide composed of five amino acids, which can inhibit the adhesion of tumor cells to laminin and vitonectin substrates. The study in rats provides the first evidence of its effectiveness in improving ischemic acute renal failure. c(RGDfV)also inhibits renal tubular obstruction by preventing intercellular adhesion, and experiments show that cyclic peptide c(RGDfV) can also be used to prevent retinal neovascularization; Secondly,c(RGDfV) can also bind to avb3 receptor.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | cyclo(RGDfV) |
Sequence(3-letter code) | cyclo (Arg-Gly-Asp-d-Phe-Val) |
Peptide Structure | 
|
Molecular Formula | C26H38N8O7 |
Molecular Weight | 574.63 |
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关键字： 137813-35-5;细胞粘附抑制剂多肽;c(RGDfV);RGD环肽;多肽;
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