一般描述
Phosphatidylcholine (PC) is one of the most important constituent of the mucosal layer of the colon. 08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) is a water soluble short alkyl chain lipid. The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
应用
08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) has been used as a substrate to study the analytical capabilities of several methods to determine water soluble phospholipids containing choline (wCh-PL) and also to study the behavior of the its analytical signal in a synthetic serum matrix (data-Trol). It may also be used as a bicellar model to study their phase behavior and to form a lipid film to study its effect on P-glycoprotein′s (P-gp′s) activity/to compare its effect with TWEEN®80 and Cremophor®EL.
生化/生理作用
Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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