Product Name：Retatrutide
CAS No.：2381089-83-2
Synonyms：LY3437943；GIPR/GLP-1R/GCGR激动剂多肽
Catalog No.：218P021
Brand：HongTide（上海鸿肽）
Description：Retatrutide (LY3437943)是胰高血糖素受体(GCGR)、葡萄糖依赖性促胰岛素多肽受体(GIPR)和胰高血糖素样肽-1受体 (GLP-1R)的三重激动剂肽，是由约40个氨基酸组成的多肽，序列中含有双靶点。Retatrutide抑制人GCGR、GIPR和GLP-1R，EC50值分别为5.79、0.0643和0.775nM。Retatrutide可用于肥胖的研究。
Retarutide (LY3437943) is a triple agonist peptide of glucagon receptor (GCGR), glucose-dependent insulin-promoting peptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). It is a peptide composed of about 40 amino acids and contains double targets in its sequence. Retarutide inhibited human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775nM, respectively. Retarutide can be used for obesity research.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Y-{Aib}-QGTFTSDYSI-{α-Me-L}-LDKK((AEEA)-γ-Glu-C20 diacid)AQ-{Aib}-AFIEYLLEGGPSSGAPPPS-NH2 |
Sequence(3-letter code) | H-Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
Peptide Structure | 
|
Molecular Formula | C221H342N46O68 |
Molecular Weight | 4731.33 |
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邮箱：sales1@hongtide.com
关键字： 2381089-83-2;Retatrutide;LY3437943;GIPR/GLP-1R/GCGR激动剂;多肽;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。