Product Name:Certepetide
CAS No.:2580154-02-3
Synonyms:CEND-1;iRGD;NRP-1激活剂
Catalog No.:218P024
Brand:HongTide(上海鸿肽)
Description:Certepetide (CEND-1)是一种双功能环肽 (a.k.a. iRGD),是由9个氨基酸组成的环状多肽,序列中含有一对二硫键。Certepetide是一种可穿透肿瘤的多肽,其RGD motif可与α-V整联蛋白 (alphav-integrins)相互作用,并激活神经纤毛蛋白1 (NRP-1),从而将实体瘤微环境转化为临时药物管道。Certepetide可在肿瘤中累积,可用于胰腺癌和其他实体瘤的研究。
Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD), which is a cyclic peptide composed of 9 amino acids and contains a pair of disulfide bonds in its sequence. Certepetide is a peptide that can penetrate tumor, and its RGD motif can α- V integrins interact with each other and activate neurociliary protein 1 (NRP-1), thus transforming the solid tumor microenvironment into a temporary drug pipeline. Certepetide can accumulate in tumors and can be used in the research of pancreatic cancer and other solid tumors.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-CRGDKGPDC-NH2(Disulfide bridge: Cys1-Cys9) |
Sequence(3-letter code) | Ac-Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys-NH2(Disulfide bridge:Cys1-Cys9) |
Peptide Structure | ![Certepetide 2580154-02-3.png Certepetide 2580154-02-3.png](/SupplyImg/2023-03-10/6381408347195612227747291.jpg)
|
Molecular Formula | C37H60N14O14S2 |
Molecular Weight | 989.09 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 2580154-02-3;Certepetide;NRP-1激活剂;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。